What is the Recombinant Flu Vaccine?
The Recombinant Influenza Vaccine (RIV) is produced using genetic recombination technology. Unlike traditional methods, this vaccine is created without using eggs or the actual influenza virus. Instead, it utilizes genetic engineering to directly produce hemagglutinin (HA), the crucial antigenic protein found on the surface of the flu virus. This results in a vaccine with higher antigen content, excellent safety profile, and the ability to trigger a robust immune response.
According to recommendations from the Scientific Committee on Vaccine Preventable Diseases, the recombinant flu vaccine, along with inactivated and nasal spray vaccines, is recommended for use in Hong Kong, providing effective protection against seasonal influenza.
What is the Traditional Flu Vaccine?
The traditional Inactivated Influenza Vaccine (IIV) is manufactured by growing the influenza virus in chicken eggs, then inactivating (killing) the virus to create the vaccine. With a long history of safe use, this vaccine is suitable for all age groups, including children.
Key Differences: Recombinant vs. Traditional Vaccines
- 3x higher antigen content - provides stronger, longer-lasting immune protection
- 30% more effective for adults aged 50 and above
- Significantly higher antibody levels - 200% increase against H3N2, 50% increase against H1N1
- Egg-free formulation - safe for individuals with egg allergies
International Recommendations
Health authorities in the UK, US, and Hong Kong all recommend recombinant flu vaccines as a preferred choice for adults aged 65+ and high-risk groups, recognizing their added protection benefits.
Recombinant vs. Traditional Vaccine: Quick Comparison
| Feature | Traditional Vaccine (IIV) | Recombinant Vaccine (RIV) |
|---|---|---|
| Production Method | Egg-based, inactivated virus | Recombinant technology, egg-free |
| Antigen Content | ~15 μg/dose | ~45 μg/dose (3x higher) |
| Age Approval | 6 months+ | 18 years+ |
| Ideal For | General population, including children | Adults & seniors, especially those with egg allergies |
| Available Brands | Abbott Influvac Tetra (Netherlands) Sanofi Vaxigrip (France) | Sanofi Flublok (USA) |
| Allergy Considerations | Contains egg protein | Egg-free, safe for egg allergies |
| Effectiveness | Effective against multiple strains | Enhanced protection for seniors & immunocompromised |
| Price | $220 | $420 |
| Subsidized Price under VSS scheme | Free | $200 |
For detailed information about which vaccine is right for you and complete pricing details, visit our 2025/26 Flu Vaccine Guide.
Who Should Avoid the Recombinant Vaccine?
- Those with previous severe allergic reactions to any component of the recombinant vaccine
- Individuals with bleeding disorders or taking anticoagulants (consult doctor first)
- Not recommended for those under 18 years old
Are There More Side Effects?
The most common side effects are mild and temporary, including:
- Pain, redness, or swelling at injection site
- Mild fever, chills, muscle aches, or fatigue
Serious side effects are rare. Consult your doctor immediately if you experience persistent fever, difficulty breathing, mouth swelling, hives, or other concerning symptoms after vaccination.
How Long Does Protection Last? Annual Vaccination?
Like all flu vaccines, the recombinant vaccine requires annual administration to provide optimal protection against evolving seasonal flu strains.
Vaccine Features
Brand Information
We use Sanofi Flublok recombinant influenza vaccine.
Pricing
- Standard price: $420
- Government subsidized price: $200 for eligible individuals under the Vaccination Subsidy Scheme
Vaccination Process
- Health assessment with our healthcare professional
- Intramuscular injection in upper arm
- 15-minute observation period
- Resume normal activities
For detailed booking instructions and required documents, our Complete Vaccination Guide has all the information you need.
To determine which vaccine is most suitable for you and to learn about other types and their pricing, please refer to our 2025/26 Flu Vaccine Detailed Information Main Page for the most comprehensive information.
Booking and Availability Information
Booking Methods:
- Online booking system: Check our booking system for latest stock and available timeslots
>> Check Vaccine Availability Now <<
Why Choose Shoebill Health Nasal Spray Vaccine?
✅ Professional team: Administered by experienced Registered Nurses
✅ Government recognized: Participates in Vaccination Subsidy Scheme, eligible persons enjoy discounted rates
Book Now
Limited recombinant vaccine available - book early to secure your appointment.
📞 Enquiry: 9446 2963 (WhatsApp/Call)
📍 Mong Kok: Entire 1/F, 562 Nathan Road (Near MTR Yau Ma Tei Station Exit A2) View Map
📍 Wan Chai: Room 13D, Derby Commercial Building, 113-117 Wan Chai Road (Near MTR Wan Chai Station Exit A3) View Map
About Shoebill Health Care
Shoebill Health Care is committed to providing professional and reliable medical services.
We have extensive experience in community health programs, having provided vaccination services to over 200,000 people and conducted more than 2,000 outreach services for schools, businesses, and organizations.
Our team has rich clinical experience and can provide professional health assessments and nursing services for each client. Whether for individual or group vaccination needs, we can provide comprehensive solutions. For enquiries about corporate or group vaccination services, please feel free to contact us for detailed consultation.
